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Phospho-LKB1 (Thr189) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538367
Weitere Details : Netto-Gewicht : 0.00900kg
Beschreibung
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.Spezifikation
Phospho-LKB1 (Thr189) | |
Polyclonal | |
Unconjugated | |
STK11 | |
Serine/threonine-protein kinase STK11, Liver kinase B1, LKB1, hLKB1, Renal carcinoma antigen NY-REN-19, STK11, LKB1, PJS | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
20869, 6794 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q15831, Q9WTK7 | |
STK11 | |
A synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of throsine 189 (G-G-TP-L-K) | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |