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Phospho-p130Cas (Tyr165) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538377
Weitere Details : Netto-Gewicht : 0.00900kg
Beschreibung
The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.Spezifikation
Phospho-p130Cas (Tyr165) | |
Polyclonal | |
Unconjugated | |
BCAR1 | |
Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, BCAR1, CAS, CASS1, CRKAS | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
12927, 25414, 9564 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P56945, Q61140, Q63767 | |
BCAR1 | |
A synthetic phosphopeptide derived from human p130 Cas around the phosphorylation site of Tyr165 (D-L-YP-Q-V) | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |