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Phospho-PRKD2 (Ser876) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538421
Weitere Details : Netto-Gewicht : 0.00900kg
Beschreibung
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms ( alpha, betaI, betaII and gamma) and novel (n) PKC isoforms ( delta, epsilon, zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and epsilon are independent of Ca 2+. On the other hand, nPKC delta and epsilon, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.Spezifikation
Phospho-Protein Kinase D2 (Ser876) | |
Polyclonal | |
Unconjugated | |
PRKD2 | |
Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKCu, PKC u, PKC-u, Serine/threonine-protein kinase D2, nPKC-D2, PRKD2, PKD2, HSPC187, PKC mu, PKCmu, Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu, PRKD3, EPK2, PRKCN, PKD3, PKCv, PKC v, PKC-v, PKC nu, PKCnu, PKC-nu | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
101540, 25865 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q9BZL6, Q8BZ03 | |
PRKD2 | |
A synthetic phosphopeptide derived from human PKD2 around the phosphorylation site of Ser876 (R-I-SP-V-L) | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |