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PKD1/2/3/PKC mu Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538387
Weitere Details : Netto-Gewicht : 0.00900kg
Beschreibung
PKC mu (protein kinase C mu, PRKD1) is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway. In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCu. Phosphorylation at Ser916 correlates with PKD/PKCu catalytic activity. PKC mu is one of the PKC family members, and the protein binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface. Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways.Spezifikation
| PKC mu | |
| Polyclonal | |
| Unconjugated | |
| PRKD1 | |
| Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKCu, PKC u, PKC-u, Serine/threonine-protein kinase D2, nPKC-D2, PRKD2, PKD2, HSPC187, PKC mu, PKCmu, Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu, PRKD3, EPK2, PRKCN, PKD3, PKCv, PKC v, PKC-v, PKC nu, PKCnu, PKC-nu | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18760, 5587, 85421 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q15139, Q62101, Q9WTQ1 | |
| PRKD1 | |
| A synthetic non-phosphopeptide derived from human PKD1/2/3/PKC mu around the phosphorylation site of Ser744 and Ser748 (E-K-SP-F-R-R-SP-V-V) | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |