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PKD1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marke:  Invitrogen OSP00006W

Weitere Details : Netto-Gewicht : 0.01000kg

Artikelnummer. 11564873

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Beschreibung

Beschreibung

Reconstitute with 100 μL of distilled water.

This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal domit polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on chromosome 16p, have been described.
Spezifikation

Spezifikation

PKD1
Polyclonal
PKD1
Polycystin-1, PKD1, Autosomal domit polycystic kidney disease protein 1, PBP
Rabbit
100 μL
Primary
Human
Antibody
IgG
Immunohistochemistry, Western Blot
Unconjugated
P98161
PKD1
A synthetic peptide from the c-terminal region of human polycystic kidney disease protein 1
RUO
5310
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Lyophilized
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote