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STAC2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marke:  Invitrogen PA539453

Weitere Details : Netto-Gewicht : 0.00900kg

Artikelnummer. 15546351

  • 473.00 € / 100 Mikrogramm
Verfügbar ab: 07-05-2024
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Beschreibung

Beschreibung

STAC2 (SH3 and cysteine-rich domain-containing protein 2), also known as 24b2/STAC2, is a 411 amino acid protein that contains one SH3 domain and one phorbol-ester/DAG-type zinc finger. Encoding two alternatively spliced isoforms, the STAC2 gene contains over 15 thousand bases and maps to human chromosome 17q12. Human chromosome 17 comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintece of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with maligt cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determit of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Spezifikation

Spezifikation

STAC2
Polyclonal
Unconjugated
STAC2
SH3 and cysteine-rich domain-containing protein 2
Rabbit
Antigen affinity chromatography
RUO
342667
-20°C
Liquid
Western Blot
1 mg/mL
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Q6ZMT1
STAC2
A synthetic peptide derived from the internal region of human STAC2
100 μg
Primary
Human
Antibody
IgG
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote