missing translation for 'onlineSavingsMsg'
Learn More

Stat1 Mouse, Unlabeled, Clone: 42, BD

Mouse Monoclonal Antibody

251.00 € - 434.00 €

Spezifikation

Antigen Stat1
Isotyp IgG2b
Immunogen Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Rezeptur Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Konjugat Unconjugated
Mehr Spezifikationen ansehen

Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15815319
Unterlagen ansehen
BD Biosciences
610186
150μg
434.00 €
1 Set
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab
23-11-2020
Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!
15805319
Unterlagen ansehen
BD Biosciences
610185
50μg
251.00 €
1 Set
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab
23-11-2020
Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!
Beschreibung

Beschreibung

The Stat proteins function as both cytoplasmic signal transducers and activators of transcription. The Stat91/84 (the two proteins are the result of alternate splicing-Stat91 has an additional 38 C-terminal amino acids) and Stat113 were the first identified members of this protein family. These three polypeptides contain both SH2 and SH3 domains and have also been described as members of the ISGF3 (interferon-stimulated gene factor 3) complex. With the discovery of additional members of the Stat family (Stats3 & 4), the nomenclature has been revised to indicate the Stat family members in the order of their discovery. Stat 91, 84, and 113 have become Stat1α, Stat1β, and Stat2, respectively. Stat1α is present in a higher concentration than Stat1β in most cell types. In response to IFNα treatment, Stat1α, Stat1β, and Stat2 become tyrosine-phosphorylated and migrate to the nucleus where they join a 48kDa DNA binding protein and subsequently direct the transcription at IFNα responsive elements. In IFN-γ treated cells, Stat1α (but not Stat2) becomes phosphorylated and forms a dimer. It then enters the nucleus and binds to the IFN-γ activated site (GAS) element in order to direct IFN-γ activated transcription.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

Stat1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Unconjugated
Cell Biology
Murine
Affinity Purified
Monoclonal
C-Terminus
IgG2b
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
42
250μg/mL
Store undiluted at -20°C.
Sicherheitsdatenblatt (SDS)

For Research Use Only.