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SFTPD Mouse anti-Human, Biotin, Clone: 10B2, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Invitrogen HYB24604B01

Weitere Details : Netto-Gewicht : 0.01000kg

Artikelnummer. 11514372

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Beschreibung

Beschreibung

HYB 246-04B-01 is specific for SP-D from amniotic fluid, serum and bronchioalveolar lavage. HYB 246-04B-02 does not influence SP-D’s binding to carbohydrates.  HYB 246-04B-01 has been successfully used in ELISA and Western blot procedures. HYB 246-04B-01 is suitable as detection antibody in sandwich ELISA in combination with a polyclonal antibody against SP-D. Binding of HYB 246-04B-01 is Ca++ dependent. In Western blotting after SDS-PAGE HYB 246-04B-01 reacts with non-reduced SP-D only. The HYB 246-04B-01 immunogen is native human SP-D purified from late pregcy amniotic fluid. Epitope of HYB 246-04B-01 is localised within the C-terminal neck CRD (carbohydrate recognition domain) of SP-D. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular ′head′ regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins man-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages. The serum concentration is approximately 700 ng/mL in healthy individuals.
Spezifikation

Spezifikation

SFTPD
Monoclonal
1 mg/mL
SFTPD
Pulmonary surfactant-associated protein D, SP-D, PSP-D, COLEC7, Collectin7, Pulmonary surfactant apoprotein, SFTP4, SFTPD, Surfactant associated prote
Mouse
Purified
RUO
6441
4° C
Liquid
ELISA, Western Blot
10B2
Biotin
P35247
SFTPD
Native human SP-D purified from late pregcy amniotic fluid.
100 μL
Primary
Human
Antibody
IgG2a
Produktvorschläge

Produktvorschläge

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