missing translation for 'onlineSavingsMsg'
Learn More

Syk Mouse anti-Human, Clone: 8H5, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Invitrogen MA517206

Weitere Details : Netto-Gewicht : 0.01000kg

Artikelnummer. 15378170

Dieser Artikel ist im Moment nicht verfügbar oder wird nicht mehr hergestellt.
Schauen Sie bitte auf unsere Produktseite nach möglichen Alternativen


Beschreibung

Beschreibung

A suggested positive control for this product is THP-1 cells.

Syk, Spleen tyrosine kinase, is expressed in a wide range of hematopoietic and non-hematopoietic cells and plays a key role in adaptive immune system, which is the immunoreceptor (B cell receptor and Fc-receptors) signaling pathways including Fcgamma receptor-mediated phagocytosis. In hematopoietic cells such as B and T lymphocytes, natural killer cells, mast cells, macrophages and platelets, Syk is involved in the proximal signaling downstream of activated immunoreceptors (e.g. BCR, TCR, Fc receptors) containing immunoreceptor tyrosine-based activation motifs (ITAMs) to which it binds using its tandem SH2 domains. Activated and autophosphorylated Syk then phosphorylates its specific substrates including other enzymes and adaptor proteins, orchestrating a complex series of cellular responses such as cell proliferation, differentiation, survival and phagocytosis.
Spezifikation

Spezifikation

SYK
Monoclonal
Unconjugated
SYK
Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-syk
Mouse
Ammonium sulfate precipitation
RUO
6850
-20°C
Liquid
ELISA, Immunoprecipitation
8H5
HEPES with 0.01% BSA, 0.15M NaCl, 50% glycerol and 0.03% sodium azide
P43405
SYK
Synthetic peptide
100 μL
Primary
Human
Antibody
IgG1
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote