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VWF Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Marke:  Invitrogen PA516634

Weitere Details : CAS : 69-74-9 Netto-Gewicht : 0.01000kg

Artikelnummer. 11335823

  • 220.00 € / 500 Mikroliter

Verfügbar ab
01-02-2021

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Beschreibung

Beschreibung

Factor VIII related antigen or von Willebrand factor is a multimeric glycoprotein. It has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. von Willebrand factor is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. As not all endothelial cells synthesize/ store) this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or maligt. Staining for factor VIII related antigen has also been used to measure angiogenesis, an indicator of tumor recurrence.
Spezifikation

Spezifikation

VWF
Polyclonal
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Q8CIZ8, P04275
coagulation factor VIII VWF
Rabbit
IgG
500 μL
4° C
Primary
22371, 7450
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
VWF
Liquid
VWF
Purified factor VIII related antigen/von Willebrand factor
Purified
RUO
Antibody
Polyclonal
Human, Mouse
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation