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Invitrogen™ ARMET Polyclonal Antibody

Beschreibung
Recommended positive controls: 293T, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (99%), Zebrafish (84%), Pig (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Spezifikation
Spezifikation
| Antigen | ARMET |
| Anwendungen | Western Blot, Immunocytochemistry |
| Klassifikation | Polyclonal |
| Konzentration | 1 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 40% glycerol and 0.01% thimerosal; pH 7 |
| Gen | MANF |
| Gen-Zugriffsnummer | P55145 |
| Gen-Alias | 3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET |
| Gensymbole | MANF |
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