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ATG5 Mouse anti-Human, Mouse, Clone: 3G6E6, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech 60061-1-IG-150UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16887015

  • 329.85 € / 150 Mikroliter

Verfügbar ab
16-06-2021

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Beschreibung

Beschreibung

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.
Spezifikation

Spezifikation

ATG5
3G6E6
Unconjugated
ATG5
Liquid
ATG5
ATG5 Fusion Protein Ag0214
Caprylic Acid Precipitation
RUO
Antibody
Monoclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
0.79 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q99J83, Q9H1Y0
APG5, APG5 LIKE, APG5L, Apoptosis specific protein, ASP, ATG5, Autophagy protein 5, hAPG5
Mouse
IgM
150 μL
-20°C
Primary
11793, 9474
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation