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Tocris Bioscience™ AZD 7762 hydrochloride

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2

N.V.

Spezifikation

Reinheit >98%
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Beschreibung

Beschreibung

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2 (IC50 vales are 5 nM for both kinases); displays at least >10 fold selectivity over a panel of 164 kinases. Potentiates cytotoxicity of DNA-damaging agents. Active in vivo. Also improves efficiency of CRISPR-Cpf1-mediated genome editing in hPSC lines (2.7-fold at 1 μM).
Spezifikation

Spezifikation

>98%
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Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Produktzertifizierungen

For Research Use Only