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Tocris Bioscience™ BAG 956
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
N.V.
Spezifikation
Reinheit | 98% |
---|---|
Inhalt und Lagerung | Store at -20°C |
Produkttyp | BAG 956 |
Molekulargewicht | 427.5 |
Hemmstoffe | BAG 956 |
Beschreibung
Dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.Spezifikation
98% | |
BAG 956 | |
BAG 956 |
Store at -20°C | |
427.5 |
For Research Use Only