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Beta Arrestin 2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 10171-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16886373

  • 112.71 € / 20 Mikroliter

Voraussichtliches Versanddatum: 25-06-2021

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Beschreibung

Beschreibung

Beta-arrestin-2, or ARRB2, is an adaptor protein belonging to the arrestin family with an N- arrestin domain and a C- arrestin domain. ARRB2 is a regulatory protein involved in heterotrimeric G protein-coupled receptor desensitization and is known to regulate beta2-adrenergic receptor (beta2AR) function by enhancing beta2AR mediated nuclear translocation of ERK. ARRB2 binds to phosphorylated beta2ARs, thereby causing a significant impairment of their capacity to activate G(S) proteins. Along with AIP4, ARRB2 acts as an endosomal sorting molecule that mediates CXCR4 entry into a degradative pathway. It may also be involved in hormone-specific desensitization of TSH receptors. ARRB2 is a Ca2+ binding protein of the retinal outer segments and binds to P-rhodopsin and is also involved in synaptic transmission in photoreceptor cells. It is widely expressed in most of the tissues, especially neuronal tissues and spleen.
Spezifikation

Spezifikation

Beta Arrestin 2
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P32121, Q91YI4
ARB2, ARR2, ARRB2, Arrestin beta 2, arrestin, beta 2, BARR2, Beta arrestin 2
Rabbit
IgG
20 μL
-20°C
Primary
216869, 409
Western Blot, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunocytochemistry
Unconjugated
ARRB2
Liquid
ARRB2
Beta Arrestin 2 Fusion Protein Ag0227
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate