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BIBX 1382 dihydrochloride, Tocris Bioscience™

Highly selective EGFR-kinase inhibitor

Marke:  RD Systems (Bio-Techne) 24161

Weitere Details : CAS : 196612-93-8 Netto-Gewicht : 0.01000kg

Menge. 1mg

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Artikelnummer. 13411174

  • 173.46 € / 1 Milligramm

Voraussichtlicher Liefertermin 29-10-2019

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Beschreibung

Beschreibung

Potent, selective inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM). Displays > 1000-fold lower potency against ErbB2 (IC50 = 3.4 μM) and a range of other related tyrosine kinases (IC50 > 10 μM). Oral administration inhibits growth of established human xenografts in athymic mice.
Spezifikation

Chemische Identifikatoren

1216920-18-1
460.763
falnidamol dihydrochloride, dsstox_cid_26307, dsstox_rid_81528, dsstox_gsid_46307, n8-3-chloro-4-fluorophenyl-n2-1-methyl-4-piperidinyl-pyrimido 5,4-d pyrimidine-2,8-diamine dihydrochloride, bibx 1382 dihydrochloride, n8-3-chloro-4-fluorophenyl-n2-1-methyl-4-piperidinyl-pyrimido 5,4-d pyrimidine-2,8-diamine dihydrochloride; 8-3-chloro-4-fluoroanilino-2-1-methyl-4-piperidyl amino pyrimido 5,4-d pyrimidine; falnidamol; falnidamol inn, n8-3-chloro-4-fluorophenyl-n2-1-methylpiperidin-4-yl pyrimido 5,4-d 1,3 diazine-2,8-diamine dihydrochloride, n8-3-chloro-4-fluorophenyl-n2-1-methylpiperidin-4-yl pyrimido 5,4-d pyrimidine-2,8-diamine dihydrochloride
4-N-(3-chloro-4-fluorophenyl)-6-N-(1-methylpiperidin-4-yl)pyrimido[5,4-d]pyrimidine-4,6-diamine;dihydrochloride
C18H21Cl3FN7
RFXGEKWBTCMDAW-UHFFFAOYSA-N
46861540
CN1CCC(CC1)NC2=NC=C3C(=N2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl.Cl.Cl

Spezifikation

1mg
1216920-18-1
falnidamol dihydrochloride, dsstox_cid_26307, dsstox_rid_81528, dsstox_gsid_46307, n8-3-chloro-4-fluorophenyl-n2-1-methyl-4-piperidinyl-pyrimido 5,4-d pyrimidine-2,8-diamine dihydrochloride, bibx 1382 dihydrochloride, n8-3-chloro-4-fluorophenyl-n2-1-methyl-4-piperidinyl-pyrimido 5,4-d pyrimidine-2,8-diamine dihydrochloride; 8-3-chloro-4-fluoroanilino-2-1-methyl-4-piperidyl amino pyrimido 5,4-d pyrimidine; falnidamol; falnidamol inn, n8-3-chloro-4-fluorophenyl-n2-1-methylpiperidin-4-yl pyrimido 5,4-d 1,3 diazine-2,8-diamine dihydrochloride, n8-3-chloro-4-fluorophenyl-n2-1-methylpiperidin-4-yl pyrimido 5,4-d pyrimidine-2,8-diamine dihydrochloride
CN1CCC(CC1)NC2=NC=C3C(=N2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl.Cl.Cl
460.763
460.77
BIBX 1382 dihydrochloride
C18H21Cl3FN7
RFXGEKWBTCMDAW-UHFFFAOYSA-N
4-N-(3-chloro-4-fluorophenyl)-6-N-(1-methylpiperidin-4-yl)pyrimido[5,4-d]pyrimidine-4,6-diamine;dihydrochloride
46861540
>97%
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