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ACROBiosystems Biotinylated Human GM-CSF, epitope tag free, ultra sensitivity (primary amine labeling)

347.90 € - 1667.52 €

Spezifikation

Zugriffsnummer NP_000749.2
Molekulargewicht 14.5 kDa
Quelle MABSol™ Biotinylated Human GM-CSF, epitope tag free, primary amine labeling (GMF-H8214) is expressed from human HEK293 cells. It contains AA Ala 18 - Glu 144 (Accession # NP_000749.2). It is the biotinylated form of ActiveMax™ Human GM-CSF, Tag Free (GMF-H4214).
Immunogen Ala 18 - Glu 144
Lagerungsbedingungen -20°C
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15806867
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ACROBiosystems
GMF-H8214-25UG
25 μg
347.90 €
25 Mikrogramm
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Verfügbar ab: 08-04-2024
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15896857
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ACROBiosystems
GMF-H8214-200UG
200 μg
1667.52 €
200 Mikrogramm
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Verfügbar ab: 08-04-2024
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Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!
Beschreibung

Beschreibung

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is also known as Colony stimulating factor 2 (granulocyte-macrophage), is a cytokine initially characterized by its ability to induce colonies of granulocytes and macrophages from myeloid progenitor cells, and is secreted by macrophages, T cells, mast cells, endothelial cells and fibroblasts. GM-CSF is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Monocytes exitthe circulation and migrate into tissue, whereupon they mature into macrophages and dendritic cells. Thus, it is part of the immune/inflammatory cascade, by which activation of a small number of macrophages can rapidly lead to an increase in their numbers, a process crucial for fighting infection. The active form of the protein is found extracellularly as a homodimer. Human GM-CSF glycosylated in its mature form. As a part of the immune/inflammatory cascade, GM-CSF promotes Th1 biased immune response, angiogenesis, allergic inflammation, and the development of autoimmunity, and thus worthy of consideration for therapeutic target. GM-CSF has also recently been evaluated in clinical trials for its potential as a vaccine adjuvant in HIV-infected patients. The preliminary results have been promising. GM-CSF is also used as a medication to stimulate the production of white blood cells following chemotherapy.

The product does NOT contain any epitope tags. The protein has a calculated MW of 14.5 kDa. The protein migrates as 18-28 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Spezifikation

Spezifikation

NP_000749.2
MABSol™ Biotinylated Human GM-CSF, epitope tag free, primary amine labeling (GMF-H8214) is expressed from human HEK293 cells. It contains AA Ala 18 - Glu 144 (Accession # NP_000749.2). It is the biotinylated form of ActiveMax™ Human GM-CSF, Tag Free (GMF-H4214).
-20°C
GM-CSF
Human
PBS, pH7.4
HEK293
MABSol™ Biotin Labeled Proteins
14.5 kDa
Ala 18 - Glu 144
GM-CSF,CSF2,MGC131935
UltraLys
Tag Free
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

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