missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Biotinylated Mouse FOLR1 Protein, His, Avitag™

Biotinylated Protein

419.88 € - 1847.47 €

Spezifikation

Zugriffsnummer NP_032060.2
Molekulargewicht 26.9 kDa
Quelle Biotinylated Mouse FOLR1, His,Avitag (FO1-M82E9) is expressed from human 293 cells (HEK293). It contains AA Thr 25 - Ser 232 (Accession # P35846-1).
Immunogen Thr 25 - Ser 232
Lagerungsbedingungen -20°C
Mehr Spezifikationen ansehen

Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15836787
Unterlagen ansehen Aktionsdetails
ACROBiosystems
FO1-M82E9-200UG
200 μg
1847.47 €
200 Mikrogramm
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 08-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!
15846787
Unterlagen ansehen Aktionsdetails
ACROBiosystems
FO1-M82E9-25UG
25 μg
419.88 €
25 Mikrogramm
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 08-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Bitte Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute!
Beschreibung

Beschreibung

Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 26.9 kDa. The protein migrates as 32-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_032060.2
Biotinylated Mouse FOLR1, His,Avitag (FO1-M82E9) is expressed from human 293 cells (HEK293). It contains AA Thr 25 - Ser 232 (Accession # P35846-1).
-20°C
FOLR1
Mouse
PBS, pH7.4
HEK293
MABSol™ Biotin Labeled Proteins
26.9 kDa
Thr 25 - Ser 232
FOLR-1,FBP,FOLR
Precision Avi
His Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Produktzertifizierungen