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CCT 018159, Tocris Bioscience™

Hsp90 inhibitor

Marke:  Tocris (Bio-Techne) 243550

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13411204

  • 810.20 € / 50 Milligramm


Voraussichtlicher Liefertermin 27-06-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC 50 = 5.7 μM) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression.
Spezifikation

Chemische Identifikatoren

171009-07-7
352.39
6-4-2,3-dihydro-1,4-benzodioxin-6-yl-5-methyl-1,2-dihydropyrazol-3-ylidene-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one, kinome_3591, owpmenvyxdjdow-uhfffaoysa-n, 4-4-2,3-dihydro-benzo 1,4 dioxin-6-yl-5-methyl-1h-pyrazol-3-yl-6-ethyl-benzene-1,3-diol
6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one
C20H20N2O4
BBTMGPQSLSYPHE-UHFFFAOYSA-N
6749166
CCC1=CC(=C2C(=C(NN2)C)C3=CC4=C(C=C3)OCCO4)C(=O)C=C1O

Spezifikation

CCT 018159
171009-07-7
6-4-2,3-dihydro-1,4-benzodioxin-6-yl-5-methyl-1,2-dihydropyrazol-3-ylidene-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one, kinome_3591, owpmenvyxdjdow-uhfffaoysa-n, 4-4-2,3-dihydro-benzo 1,4 dioxin-6-yl-5-methyl-1h-pyrazol-3-yl-6-ethyl-benzene-1,3-diol
CCC1=CC(=C2C(=C(NN2)C)C3=CC4=C(C=C3)OCCO4)C(=O)C=C1O
352.39
352.39
50mg
C20H20N2O4
BBTMGPQSLSYPHE-UHFFFAOYSA-N
6-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-4-ethyl-3-hydroxycyclohexa-2,4-dien-1-one
6749166
>98%
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