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CD205 Rat anti-Mouse, PE, Clone: 205yekta, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 12-2051-80

Weitere Details : Netto-Gewicht : 0.25000kg

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Artikelnummer. 15258719

  • 116.00 € / 25 Mikrogramm

Verfügbar ab
26-05-2021

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Beschreibung

Beschreibung

Description: The 205yekta antibody reacts with mouse CD205, also known as DEC-205 (dendritic and epithelial cells, 205 kDa). CD205 is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 has been shown to bind to PE-Cy5.5 antibody and streptavidin conjugates; therefore, this format should not be used on CD205+ dendritic cells. Applications Reported: This 205yekta antibody has been reported for use in flow cytometric analysis. Applications Tested: This 205yekta antibody has been tested by flow cytometric analyis of mouse bone marrow cells. This can be used at less than or equal to 0.03 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells. CD205 acts as an endocytic receptor that directs captured antigens to the extracellular space towards a specialized antigen processing region. Further, CD205 also prompts the reduced proliferation of B lymphocytes. Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
Spezifikation

Spezifikation

CD205
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q60767
RP23-10L17.4, CD205, DEC-205, ly-75, CLEC13B, GP200-MR6, DCL-1 fusion, LY75-CD302 fusion protein
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
205yekta
PE
Ly75
Liquid
Ly75
IgG2a, kappa
25 μg
4° C, store in dark, DO NOT FREEZE!
Primary
17076
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.