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CD266 (TWEAK Receptor) Monoclonal Antibody (ITEM-1), PE, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 12-9019-41

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 16340634

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Beschreibung

Beschreibung

Description: The ITEM-1 mAb reacts with human TWEAK Receptor/Fn14 (fibroblast growth factor-inducible 14 kDa protein). Fn14 is distantly related to the TNFR family, containing one cysteine-rich domain in the extracellular region and a TNFR-associated factor binding domain but does not contain a death domain (DD) cytoplasmic region. Fn14 plays a role in TWEAK-induced endothelial cell migration, proliferation, and angiogenesis. TWEAK-induced cell death via Fn14 includes both apoptosis and necrosis and can be blocked by an anti-TWEAK antibody, CARL-1. Fn14 is expressed on HUVEC and in some cancer tissues but not on freshly isolated PBMCs. Fn14 mRNA expression has been identified during liver regeneration. Applications Reported: This ITEM-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This ITEM-1 antibody has been pre-diluted and tested by flow cytometric analysis of human Fn14 transfected L5178Y cells. This may be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser

CD266 (TWEAK Receptor) Monoclonal antibody specifically detects CD266 (TWEAK Receptor) in Human samples. It is validated for Flow Cytometry
Spezifikation

Spezifikation

CD266 (TWEAK Receptor)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9NP84
TNFRSF12A
Affinity chromatography
RUO
51330
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
ITEM-1
PE
TNFRSF12A
AI255180; BOS_22618; C87282; CD266; FGF-inducible 14; Fgfrp2; Fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; Fn14; HPIP; Tnfrsf12a; Tumor necrosis factor receptor superfamily member 12A; TWEAKR; TWEAK-R; Tweak-receptor
Mouse
25 Tests
Primary
Human
Antibody
IgG1 κ
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote