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CD268 (BAFF Receptor) Rat anti-Mouse, FITC, Clone: eBio7H22-E16, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 11-5943-81

Weitere Details : Netto-Gewicht : 0.25000kg

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Artikelnummer. 15278299

  • 86.75 € / 50 Mikrogramm

Verfügbar ab
28-04-2021

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Beschreibung

Beschreibung

Description: The monoclonal antibody eBio7H22.E16 reacts with mouse BAFF-Receptor, a type III transmembrane TNF receptor family member. BAFF-R was found to be the predomit BAFF receptor expressed on peripheral B cells, in both humans and mice. The receptor is found on the surface of all B220+ B cells found in spleen. BAFF-R is expressed on activated/memory subsets of T-cells and is important for splenic B cell maturation and survival and is a major mediator of BAFF- dependent costimulatory responses in peripheral B and T cells. BAFF-R can cause a high level of autoimmune disease and a defect in BAFF-R will cause a decrease in generating mature B-Cells The ligand for the BAFF-R is BAFF also known as BLyS. Applications Reported: This eBio7H22-E16 antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio7H22-E16 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered.

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells.
Spezifikation

Spezifikation

CD268 (BAFF Receptor)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9D8D0
TNFRSF13C, BAFF-R, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor, BAFF-R, BLyS receptor 3, TNFRSF13C, BAFFR, BR3
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
eBio7H22-E16
FITC
Tnfrsf13c
Liquid
Tnfrsf13c
IgG1, kappa
50 μg
4° C, store in dark, DO NOT FREEZE!
Primary
72049
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.