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CD278 (ICOS) Monoclonal Antibody (7E.17G9), Super Bright™ 645, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
133.00 € - 345.00 €
Spezifikation
Antigen | CD278 (ICOS) |
---|---|
Klon | 7E.17G9 |
Konzentration | 0.2 mg/mL |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15913684
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Affymetrix eBioscience
64-9942-82 |
100 μg |
345.00 €
100 Mikrogramm |
Verfügbar ab: 06-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15903684
|
Invitrogen
64-9942-80 |
25 μg |
Dieser Artikel ist im Moment nicht verfügbar oder wird nicht mehr hergestellt. Schauen Sie bitte auf unsere Produktseite nach möglichen Alternativen |
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Beschreibung
Description: The ISA-3 monoclonal antibody reacts with human ICOS (Inducible COStimulatory molecule), also known as H4, CRP-1 and AILIM. ICOS is a T cell specific activation molecule and a third member of the CD28/CTLA-4 family. Human ICOS has a relative molecular mass of 55-60 kDa, composed of 27 kDa and 29 kDa chains. Human ICOS on activated T cells has potent costimulatory activity for T cell activation and is required for humoral immune responses, in particular for memory B cell and plasma cell generation. ICOS binds to its ligand, B7h/B7RP-1 expressed on activated APCs (antigen presenting cells) and on a number of inflamed peripheral tissues. Plate-bound ISA-3 is costimulatory for T cells and induces production of IL-4, IL-5, IL-10 and other cytokines, but not IL-2. ISA-3 has the same reactivity pattern and characteristics as F44. ISA-3 was generated against the human ICOS antigen. C398.4A, anti-mouse ICOS/H4 (cat. 14-9949), was shown to cross-react with human ICOS but binds to an epitope different from ISA-3. C398.4A stains activated cells brighter than ISA-3; however, it also exhibits higher staining of non-activated human peripheral blood or isolated PBMC. To achieve the brightest staining of ICOS on activated human T cells, please use 13-9948 or 12-9948 rather than 11-9948. Applications Reported: This ISA-3 antibody has been reported for use in flow cytometric analysis.
CD278 (ICOS) Monoclonal antibody specifically detects CD278 (ICOS) in Mouse samples. It is validated for Flow Cytometry.Spezifikation
CD278 (ICOS) | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
Q9WVS0 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
7E.17G9 | |
Flow Cytometry | |
Super Bright 645 | |
Rat | |
Mouse | |
54167 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |