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CD366 (TIM3) Monoclonal Antibody (F38-2E2), Super Bright™ 436, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

343.00 €

Spezifikation

Antigen CD366 (TIM3)
Klon F38-2E2
Konzentration 5 μL/Test
Anwendungen Flow Cytometry
Klassifikation Monoclonal
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Produkte 1
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
16331254
Unterlagen ansehen Aktionsdetails
Affymetrix eBioscience
62-3109-42
100 Tests
343.00 €
100 Stück
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Beschreibung

Beschreibung

Description: This F38-2E2 monoclonal antibody reacts with human CD366, also known as T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) or HAVCR2.  This cell surface receptor is expressed on activated CD4+ T cell subsets (e.g. Th1, Th17, and Treg), CD8+ T cells, monocytes, dendritic cells, and mast cells.  Due to alternative splicing, CD366 exists as membrane-bound and soluble forms.  Galectin-9 has been identified as the ligand for CD366.  In humans, this receptor negatively regulates CD4+  T cells, influencing the secretion of some Th1- and Th17-related cytokines.  CD366 has also been implicated in tolerance, autoimmune disease (e.g. multiple sclerosis), and HIV infection. Applications Reported: This F38-2E2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This F38-2E2 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome.

CD366 (TIM3) Monoclonal antibody specifically detects CD366 (TIM3) in Human samples. It is validated for Flow Cytometry.
Spezifikation

Spezifikation

CD366 (TIM3)
5 μL/Test
Monoclonal
Liquid
RUO
Q8TDQ0
IgG1 κ
Affinity chromatography
Antibody
F38-2E2
Flow Cytometry
Super Bright 436
Mouse
Human
84868
Primary
4° C, store in dark, DO NOT FREEZE!
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Produktzertifizierungen

For Research Use Only.