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CD41a, PE, clone: eBioMWReg30 (MWReg30), eBioscience™

Rat Monoclonal Antibody

89.25 € - 270.00 €

Spezifikation

Antigen CD41a
Klon eBioMWReg30 (MWReg30)
Target Species Murine
Konjugat PE
Isotyp IgG1, kappa, kappa
Mehr Spezifikationen ansehen

Produkte 3
Produktcode Marke Menge. Preis Menge & Verfügbarkeit  
Produktcode Marke Menge. Preis Menge & Verfügbarkeit  
15228529 Affymetrix eBioscience
12-0411-81
50μg 89.25 €
50 Mikrogramm
Auf Lager: 1
Zum Warenkorb hinzufügen
15238529 Affymetrix eBioscience
12-0411-82
100μg 180.00 €
100 Mikrogramm
Auf Lager: 2
Zum Warenkorb hinzufügen
15248529 Affymetrix eBioscience
12-0411-83
200μg 270.00 €
200 Mikrogramm
Voraussichtlicher Liefertermin 24-01-2019
Zum Warenkorb hinzufügen
Beschreibung

Beschreibung

Description: The eBioMWReg30 monoclonal antibody reacts with mouse CD41 (fibrinogen receptor, gpIIb, integrin alpha IIb). While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and adult. CD41 associates with CD61 (gpIIIa, integrin beta III) to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells (HSC). Specifically, it was found that CD150+CD48- bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore, the efficiency of reconstitution was enhanced when HSCs were further enriched through the exclusion of CD41+ cells. Thus, the use of CD150+CD48-CD41- as an expression profile efficiently identifies hematopoietic stem cells.Applications Reported: This eBioMWReg30 (MWReg30) antibody has been reported for use in flow cytometric analysis.Applications Tested: This eBioMWReg30 (MWReg30) antibody has been tested by flow cytometric analysis of mouse platelets. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Spezifikation

Spezifikation

CD41a
Murine
IgG1, kappa, kappa
Monoclonal
Liquid
Antibody
Store at 2-8°C. Do not freeze. Light-sensitive material.
eBioMWReg30 (MWReg30)
PE
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.