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CH 223191, Tocris Bioscience™

Potent aryl hydrocarbon receptor (AhR) antagonist

Marke:  Tocris (Bio-Techne) 385810

Weitere Details : Netto-Gewicht : 0.01000kg

Menge. 10mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13413714

  • 211.20 € / 10 Milligramm


Voraussichtlicher Liefertermin 01-08-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Potent aryl hydrocarbon receptor (AhR) antagonist (IC50 = 30 nM). Exhibits no AhR agonist-like activity (at concentrations up to 100 μM). Inhibits 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced AhR-dependent transcription in vitro and reduces TCDD-induced toxicity in vivo. Attenuates Th17 differentiation of naive CD4 T cells and promotes expansion of hematopoietic stem cells in vitro.
Spezifikation

Chemische Identifikatoren

301326-22-7
333.395
ahr antagonist, unii-hye7315z4c, 2-methyl-2h-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazo-phenyl-amide, 2-methyl-2h-pyrazole-3-carboxylic acid-2-methyl-4-o-tolyl-azophenyl-amide, 1-methyl-n-2-methyl-4-e-2-methylphenyl diazenyl phenyl-1h-pyrazole-5-carboxamide, 2-methyl-n-2-methyl-4-e-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 2-methyl-n-2-methyl-4-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-methylphenyl azo phenyl, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phenyl, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phen yl-1h-pyrazole-5-carboxamide
2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
C19H19N5O
LKTNEXPODAWWFM-UHFFFAOYSA-N
3091786
CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C

Spezifikation

CH 223191
301326-22-7
ahr antagonist, unii-hye7315z4c, 2-methyl-2h-pyrazole-3-carboxylic acid 2-methyl-4-o-tolylazo-phenyl-amide, 2-methyl-2h-pyrazole-3-carboxylic acid-2-methyl-4-o-tolyl-azophenyl-amide, 1-methyl-n-2-methyl-4-e-2-methylphenyl diazenyl phenyl-1h-pyrazole-5-carboxamide, 2-methyl-n-2-methyl-4-e-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 2-methyl-n-2-methyl-4-2-2-methylphenyl diazen-1-yl phenyl pyrazole-3-carboxamide, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-methylphenyl azo phenyl, 1h-pyrazole-5-carboxamide, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phenyl, 1-methyl-n-2-methyl-4-2-2-methylphenyl diazenyl phen yl-1h-pyrazole-5-carboxamide
CC1=CC=CC=C1N=NC2=CC(=C(C=C2)NC(=O)C3=CC=NN3C)C
333.395
333.39
10mg
C19H19N5O
LKTNEXPODAWWFM-UHFFFAOYSA-N
2-methyl-N-[2-methyl-4-[(2-methylphenyl)diazenyl]phenyl]pyrazole-3-carboxamide
3091786
>98%
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