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Invitrogen™ CHD1L Recombinant Rabbit Monoclonal Antibody (JG35-44)

Beschreibung
Positive Control: HepG2, human tonsil tissue, human colon cancer tissue, mouse testis tissue, HepG2.
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).
Spezifikation
Spezifikation
| Antigen | CHD1L |
| Anwendungen | Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot |
| Klassifikation | Recombinant Monoclonal |
| Klon | JG35-44 |
| Konzentration | 1 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 |
| Gen | CHD1L |
| Gen-Zugriffsnummer | Q86WJ1 |
| Gen-Alias | 4432404A22Rik; ALC1; amplified in liver cancer 1; amplified in liver cancer protein 1; CHD1L; CHDL; chromodomain helicase DNA binding protein 1 like; chromodomain helicase DNA binding protein 1-like; chromodomain-helicase-DNA-binding protein 1-like; LOW QUALITY PROTEIN: chromodomain-helicase-DNA-binding protein 1-like; Snf2p; Unknown (protein for MGC:128792) |
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