CHOP/GADD153 Mouse anti-Human, Clone: 4D5A9, Proteintech
Mouse Monoclonal Antibody
Marke: Proteintech 60304-1-IG-20UL
Weitere Details : Netto-Gewicht : 0.00010kg
BeschreibungGADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
|CHOP; GADD153 Fusion Protein Ag7354|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|CEBPZ, CHOP, CHOP 10, CHOP10, DDIT 3, DDIT3, GADD153|