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Beschreibung
Immunogen sequence: WRSSSLLEEK MPRWAAEHRL EEKKTWLTNG FDVFECPPPK TENELLQMFY RQQEEIRRLR ELLTQREVQA KQ Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.
Spezifikation
Spezifikation
| Antigen | Coronin 2A |
| Anwendungen | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Klassifikation | Polyclonal |
| Konzentration | 1.4 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gen | CORO2A |
| Gen-Zugriffsnummer | Q92828 |
| Gen-Alias | CLIPINB; CORO2A; coronin 2A; coronin, actin binding protein, 2A; coronin, actin-binding protein, 2A; coronin-2A; coronin-like protein B; IR10; WD protein IR10; WD repeat-containing protein 2; WDR2; WD-repeat protein 2 |
| Gensymbole | CORO2A |
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