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ACROBiosystems Cynomolgus LAG-3 / CD223 Protein, Fc Tag
Marke: ACROBiosystems LA3-C5252-1MG
Weitere Details : Netto-Gewicht : 0.00001kg
Beschreibung
Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.0 kDa. The protein migrates as 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
| XP_005570011.1 | |
| 1 mg | |
| Ala 18 - His 449 | |
| LAG3,CD223,FDC | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >85% as determined by SDS-PAGE |
| 73.0 kDa | |
| Cynomolgus LAG-3, Fc Tag (LA3-C5252) is expressed from human 293 cells (HEK293). It contains AA Ala 18 - His 449 (Accession # XP_005570011.1). | |
| -20°C | |
| LAG-3 | |
| Cynomolgus Monkey | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Immune Checkpoint Proteins |