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Tocris Bioscience™ FR 180204
Selective ERK inhibitor
N.V.
Spezifikation
Reinheit | >98% |
---|---|
Produkttyp | FR 180204 |
Molekulargewicht | 327.34 |
Hemmstoffe | FR 180204 |
Beschreibung
Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα at concentrations less than 30 μM. Also inhibits TGFβ-induced AP-1 activation in Mv1Lu cells (IC50 = 3.1 μM).Spezifikation
>98% | |
FR 180204 | |
327.34 | |
FR 180204 |
For Research Use Only