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GCP4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA560279
Weitere Details : Netto-Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: ILFVGESVQM FENQNVNLTR KGSILKNQED TFAAELHRLK QQPLFSLVDF EQVVDRIRST VAEHLWKLMV EESDLLGQLK IIKDFYLLGR GELFQAFIDT AQHMLKTPPT A Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.Spezifikation
GCP4 | |
Polyclonal | |
Unconjugated | |
TUBGCP4 | |
4932441P04Rik; 76P; D2Ertd435e; gamma tubulin ring complex protein; gamma tubulin ring complex protein (76p gene); gamma-ring complex protein 76 kDa; Gamma-tubulin complex component 4; GCP4; GCP-4; Grip76; h76p; hGCP4; hGrip76; MCCRP3; RGD1306924; TUBGCP4; tubulin gamma complex associated protein 4; tubulin, gamma complex associated protein 4 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
27229 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunocytochemistry, Immunohistochemistry, Western Blot | |
0.1 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
Q9UGJ1 | |
TUBGCP4 | |
Recombinant protein corresponding to Human GCP4 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Research Use Only