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HLA class I (HLA-C) Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 15777-1-AP-150UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16885104

  • 329.85 € / 150 Mikroliter

Voraussichtliches Versanddatum: 25-06-2021

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Beschreibung

Beschreibung

HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described.
Spezifikation

Spezifikation

HLA class I (HLA-C)
0.27 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P30508
D6S204, HLA C, HLA Cw, HLA Cw12, HLA JY3, HLAC, HLA-C, HLC C, MHC class I antigen Cw*7, PSORS1
Rabbit
IgG
150 μL
-20°C
Primary
3107
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
HLA-C
Liquid
HLA-C
HLA class I (HLA-C) Fusion Protein Ag8461
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate