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ACROBiosystems Human ADAM8 / CD156a Protein, His Tag

Marke:  ACROBiosystems AD8-H5223-500UG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15885887

  • 1881.77 € / 500 Mikrogramm
Verfügbar ab: 02-01-2023
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Beschreibung

Beschreibung

Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.

Human ADAM8, His Tag fused with a polyhistidine tag at the C-terminus, has a calculated MW of 53.8 kDa, which migrates as a 180-220 kDa band in DTT-reduced SDS-PAGE due to glycosylation. Two main fragments bands are visible with apparent MW of 69-73 kDa a
Spezifikation

Spezifikation

AAI15405.1
53.8 kDa
500 µg
Ile 17 - Pro 497
ADAM8,MS2,CD156a
Unconjugated
50 mM Tris, 150 mM NaCl, pH7.5
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human ADAM8, His Tag (AD8-H5223) is expressed from human 293 cells (HEK293). It contains AA Ile 17 - Pro 497 (Accession # AAI15405.1).
-20°C
ADAM8
His Tag
Less than 1.0 EU / µg by the LAL method.
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