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ACROBiosystems Human HVEM / TNFRSF14 Protein, Fc Tag
362.89 € - 2661.24 €
Spezifikation
Zugriffsnummer | NP_003811.2 |
---|---|
Molekulargewicht | 43.5 kDa |
Quelle | Human HVEM, Fc Tag (HVM-H5258) is expressed from human 293 cells (HEK293). It contains AA Leu 39 - Val 202 (Accession # NP_003811.2). |
Immunogen | Leu 39 - Val 202 |
Lagerungsbedingungen | -20°C |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15896947
|
ACROBiosystems
HVM-H5258-1MG |
1 mg |
2661.24 €
1 Milligramm |
Verfügbar ab: 03-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
15886947
|
ACROBiosystems
HVM-H5258-100UG |
100 μg |
362.89 €
100 Mikrogramm |
Verfügbar ab: 03-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Herpesvirus entry mediator (HVEM) is also known as TNFRSF14, TR2 (TNF receptorlike molecule) and ATAR (another TRAF associated receptor), is a type I membrane protein belonging to the TNF/NGF receptor superfamily. HVEM expression has been detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. The extracellular domain of HVEM has been shown to interact directly with the herpes simplex virus envelope glycoprotein D (gD). Two TNF superfamily ligands, including the secreted TNFβ (lymphotoxin α) and the membrane protein LIGHT (lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), have been shown to be the cellular ligands for HVEM. Besides HVEM, LIGHT can also interact with LTβR, the receptor for lymphotoxin αβ heterotrimer. The role of the HVEM LIGHT /LTβ receptor ligand pair in immune function and herpesvirus pathobiology remains to be elucidated.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 43.5 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
NP_003811.2 | |
Human HVEM, Fc Tag (HVM-H5258) is expressed from human 293 cells (HEK293). It contains AA Leu 39 - Val 202 (Accession # NP_003811.2). | |
-20°C | |
HVEM | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
Immune Checkpoint Proteins |
43.5 kDa | |
Leu 39 - Val 202 | |
TNFRSF14,ATAR,HVEA,HVEM,LIGHTR,TR2,CD270 | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |