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ACROBiosystems Human Integrin alpha 4 beta 7 (ITGA4&ITGB7) Heterodimer Protein, His Tag&Tag Free
532.24 € - 4064.44 €
Spezifikation
| Zugriffsnummer | NP 000876.3 (ITGA4) and NP_000880.1 (ITGB7) |
|---|---|
| Molekulargewicht | 111.4 kDa (ITGA4) and 81.8 kDa (ITGB7) |
| Quelle | Human ITGA4&ITGB7; Heterodimer Protein, His Tag&Tag; Free (IT7-H52W4) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7) (Accession # P13612-1 (ITGA4) and P26010-1 (ITGB7)). |
| Immunogen | Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7) |
| Lagerungsbedingungen | -20°C |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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15877157
|
ACROBiosystems
IT7-H52W4-100UG |
100 μg |
532.24 €
100 Mikrogramm |
Verfügbar ab: 03-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
|
15887157
|
ACROBiosystems
IT7-H52W4-1MG |
1 mg |
4064.44 €
1 Milligramm |
Verfügbar ab: 03-05-2024 Loggen Sie sich ein, um den Lagerbestand zu sehen |
Bitte melden Sie sich an, um diesen Artikel zu kaufen. Sie benötigen ein Web-Konto? Registrieren Sie sich noch heute! | ||||
Beschreibung
Integrin alpha 4 beta 7 is an integrin family adhesion receptor that shares subunits with alpha 4 beta 1 (VLA4) and the E-Cadherin receptor, alpha E beta 7 . Integrin alpha 4 beta 7, which is critical for homing to intestinal mucosa, is induced during T cell activation in Peyer’s patches or mesenteric lymph nodes.Its expression requires signals from local dendritic and stromal cells, including secreted retinoic acid. The HIV-1 envelope protein gp120 binds to the active form of Integrin alpha 4 beta 7, and this may or may not account for the concentration of HIV-1 virus in the gut-associated lymphoid tissue (GALT). Integrin alpha 4 beta 7 may also be involved in lymphocyte trafficking in acute intestinal graft vs. host disease (GVHD).
Human ITGA4&ITGB7 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA4 and ITGB7, has a calculated MW of 111.4 kDa (ITGA4) and 81.8 kDa (ITGB7). Subunit ITGA4 is fused with an acidic tail at the C-terminus and followed by a polyhistidSpezifikation
| NP 000876.3 (ITGA4) and NP_000880.1 (ITGB7) | |
| Human ITGA4&ITGB7; Heterodimer Protein, His Tag&Tag; Free (IT7-H52W4) is expressed from human 293 cells (HEK293). It contains AA Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7) (Accession # P13612-1 (ITGA4) and P26010-1 (ITGB7)). | |
| -20°C | |
| Integrin alpha 4 beta 7 | |
| Human | |
| 50 mM Tris, 100 mM NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 111.4 kDa (ITGA4) and 81.8 kDa (ITGB7) | |
| Tyr 34 - Thr 977 (ITGA4) and Glu 20 - His 723 (ITGB7) | |
| Integrin alpha 4 beta 7,ITGA4andITGB7 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |