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ACROBiosystems Human Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free

Marke:  ACROBiosystems IT1-H52E1-1MG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887137

  • 3261.73 € / 1 Milligramm
Verfügbar ab: 05-01-2023
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Beschreibung

Beschreibung

Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition.

Human ITGAV&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB1, has a calculated MW of 112.9 kDa (ITGAV) and 83.7 kDa (ITGB1). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhisti
Spezifikation

Spezifikation

NP_002201.1 (ITGAV) and NP_002202.2 (ITGB1)
112.9 kDa (ITGAV) and 83.7 kDa (ITGB1)
1 mg
Phe 31 - Val 992 (ITGAV) and Gln 21 - Asp 728 (ITGB1)
Integrin alpha V beta 1,ITGAVandITGB1
Unconjugated
50 mM Tris, 150 mM NaCl, pH7.5
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human ITGAV&ITGB1; Heterodimer Protein, His Tag&Tag; Free (IT1-H52E1) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) and Gln 21 - Asp 728 (ITGB1) (Accession # NP_002201.1 (ITGAV) and NP_002202.2 (ITGB1)).
-20°C
Integrin alpha V beta 1
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote