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ACROBiosystems Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free

Marke:  ACROBiosystems IT3-H52E3-1MG

Weitere Details : Netto-Gewicht : 0.00001kg

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Artikelnummer. 15887147

  • 3615.28 € / 1 Milligramm
Verfügbar ab: 05-01-2023
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Beschreibung

Beschreibung

Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB3, has a calculated MW of 112.9 kDa (ITGAV) and 81.8 kDa (ITGB3). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistid
Spezifikation

Spezifikation

NP_002201.1 (ITGAV) and NP_000203.2 (ITGB3)
112.9 kDa (ITGAV) and 81.8 kDa (ITGB3)
1 mg
Phe 31 - Val 992 (ITGAV) and Gly 27 - Asp 718 (ITGB3)
Integrin alpha V beta 3,ITGAVandITGB3
Unconjugated
50 mM Tris, 150 mM NaCl, pH7.5
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human ITGAV&ITGB3; Heterodimer Protein, His Tag&Tag; Free (IT3-H52E3) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) and Gly 27 - Asp 718 (ITGB3) (Accession # NP_002201.1 (ITGAV) and NP_000203.2 (ITGB3)).
-20°C
Integrin alpha V beta 3
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote