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Invitrogen™ Human JARID1C (aa 248-333) Control Fragment Recombinant Protein

Artikelnummer. 30210777
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Menge:
100 μl
Unit Size:
100 Mikroliter
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30210777 100 μl 100 Mikroliter
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Product Code. 30210777 Supplier Invitrogen™ Supplier No. RP106111

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83807 (PA5-83807. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.; Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Zugriffsnummer P41229
Konzentration ≥5.0 mg/mL
Zur Verwendung mit (Anwendung) Blocking Assay, Control
Zusammensetzung 1 M urea, PBS with no preservative; pH 7.4
Gen-ID (Entrez) 8242
Name Human JARID1C (aa 248-333) Control Fragment
Menge 100 μl
Kennzeichnung RUO
Gen-Alias D930009K15Rik; DXS1272E; Histone demethylase JARID1C; JARID1C; JmjC domain-containing protein SMCX; jumonji, AT rich interactive domain 1 C (Rbp2 like); Jumonji, AT rich interactive domain 1 C (RBP2-like); Jumonji/ARID domain-containing protein 1 C; KDM5C; Kiaa0234; lysine (K)-specific demethylase 5 C; lysine demethylase 5 C; lysine-specific demethylase 5 C; mKIAA0234; MR x 13; MRXJ; MRXSCJ; MRXSJ; Protein SmcX; Protein Xe169; RGD1560601; sele; selected mouse cDNA on the X; SMCX; Smcx homolog, x chromosome; Smcy homolog, X-linked; XE169
Gebräuchliche Bezeichnung JARID1C
Gensymbol KDM5C
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung His-ABP-tag
Sequenz LGLMAKDKTLRKKDKEGPECPPTVVVKEELGGDVKVESTSPKTFLESKEELSHSPEPCTKMTMRLRRNHSNAQFIESYVCRMCSRG
Inhalt und Lagerung -20°C, Avoid Freeze/Thaw Cycles
Expressionssystem E. coli
Form Liquid
Reinheits- oder Qualitätsgrad >80% by SDS-PAGE and Coomassie blue staining
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