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STEMCELL Technologies Human Recombinant GRO-beta (CXCL2)

Product Code. 17169591
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Quantity:
1000 μg
25 μg
Unit Size:
1000µg
25µg
This item is not returnable. View return policy

Product Code. 17169591

Brand: STEMCELL Technologies 78112.1

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This item is not returnable. View return policy

Description

Growth-regulated oncogene beta

  • GRO (growth-regulated oncogene)-beta or CXCL2 is a member of the CXC family, which plays an integral role in recruitment and activation of neutrophils and basophils in response to tissue injury and microbial infection
  • GRO-beta and GRO-gamma are closely related to GRO-alpha and share 90% and 86% amino acid sequence homology, respectively, with GRO-alpha
  • Receptor-binding studies have demonstrated that GRO-alpha, -beta, and -gamma signal mainly through G protein-coupled receptors CXCR1 and CXCR2 (Ahuja & Murphy)
  • GRO-beta is expressed in epithelial cells, monocytes, fibroblasts, and melanocytes and is further induced during inflammatory, epithelialization, and angiogenic processes, for example during the wound healing process of human burn wounds (Zaja-Milatovic & Richmond)
  • GRO-beta also stimulates mitogenesis in certain human melanoma cells (Unemori et al.)

Specifications

Name CXCL2, GRO2, Growth regulated protein, Macrophage inflammatory protein-2α, Melanoma growth stimulatory activity, MGSAβ, MIP-2α
Quantity 25 μg
Cell Type Cancer Cells and Cell Lines; Endothelial Cells; Granulocytes and Subsets
Purity or Quality Grade ≥95%
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