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IL-2 Rat anti-Human, Alexa Fluor 532, Clone: MQ1-17H12, eBioscience

Rat Monoclonal Antibody

Marke:  Invitrogen 58-7029-41

Weitere Details : Netto-Gewicht : 0.01000kg

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Artikelnummer. 16321064

  • 149.00 € / 25 Stück

Voraussichtliches Versanddatum: 15-11-2021

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Beschreibung

Beschreibung

Description: The MQ1-17H12 antibody reacts with human interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. The MQ1-17H12 antibody is a non-neutralizing antibody. Applications Reported: This MQ1-17H12 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MQ1-17H12 antibody has been pre-diluted and tested by flow cytometric analysis of activated normal human peripheral blood cells. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Alexa Fluor 532 is excited with the Green laser (532 nm) and emits at 561 nm. This cannot be used with the Yellow-Green laser (561 nm). We recommend using a 560/14 band pass filter.  Please make sure that your instrument is capable of detecting this fluorochrome. Excitation: 532 nm; Emission: 561 nm; Laser: Green Laser

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Spezifikation

Spezifikation

IL-2
Monoclonal
5 μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P60568
IL2
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3558
Flow Cytometry
MQ1-17H12
Alexa Fluor 532
IL2
Liquid
Rat
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate