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IL12RB2 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA555000
Weitere Details : Netto-Gewicht : 0.02000kg
Beschreibung
Immunogen sequence: WKNLSVSEAR GKILHYQVTL QELTGGKAMT QNITGHTSWT TVIPRTGNWA VAVSAANSKG SSLPTRINIM NLCEAGLLAP RQVSANSEGM DNILVTWQPP RKDPSAV Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 67%.
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn′s disease and leprosy, which is thought to contribute to the inflammatory response and host defense.Spezifikation
| IL12RB2 | |
| Polyclonal | |
| Unconjugated | |
| IL12RB2 | |
| RP11-102M16.1, IL-12 receptor beta 2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, interleukin-12 receptor beta-2 chain, interleukin-12 receptor subunit beta-2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 3595 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry | |
| 1.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q99665 | |
| IL12RB2 | |
| Recombit protein corresponding to Human IL12RB2 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Research Use Only