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JIP1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 14568-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16883264

  • 112.71 € / 20 Mikroliter

Voraussichtliches Versanddatum: 25-06-2021

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Beschreibung

Beschreibung

The protein encoded by this gene is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
Spezifikation

Spezifikation

JIP1
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9R237, Q9UQF2, Q9WVI9
IB 1, IB1, Islet brain 1, JIP 1, JIP1, JNK interacting protein 1, MAPK8IP1, PRKM8IP
Rabbit
IgG
20 μL
-20°C
Primary
116457, 19099, 9479
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
MAPK8IP1
Liquid
Mapk8ip1
JIP1 Fusion Protein Ag6150
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Rat, Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate