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Ki 20227, Tocris Bioscience™

c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

Marke:  RD Systems (Bio-Techne) 4481/50

Weitere Details : Netto-Gewicht : 0.00050kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13414824

  • 1337.53 € / 50 Milligramm


Voraussichtlicher Liefertermin 25-02-2019
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Beschreibung

Beschreibung

Inhibitor of c-Fms tyrosine kinase (M-CSFR, CSF1R) (IC50 values are 2, 12, 217 and 451 nM for c-Fms, VEGFR-2, PDGFRβ and c-Kit respectively). Does not inhibit Flt3, EGFR or c-Src. Suppresses osteoclast differentiation and osteolysis in a rat bone metastasis model.
Spezifikation

Chemische Identifikatoren

623142-96-1
480.539
1-4-6,7-dimethoxyquinolin-4-yl oxy-2-methoxyphenyl-3-1-thiazol-2-yl ethyl urea, 1-4-6,7-dimethoxyquinolin-4-yloxy-2-methoxyphenyl-3-1-thiazol-2-yl ethyl urea, 1-4-6,7-dimethoxyquinolin-4-yl oxy-2-methoxyphenyl-3-1-1,3-thiazol-2-yl ethyl urea, pubchem22465, d08bjr, n-4-6,7-dimethoxy-4-quinolinyl o xy-2-methoxyphenyl-n'-1-2-thiazolyl ethyl urea, n-4-6,7-dimethoxy-4-quinolinyl oxy-2-methoxyphenyl-n'-1-2-thiazolyl ethyl urea, n-4-6,7-dimethoxy-4-quinolyl oxy-2-methoxyphenyl-n'-1-1,3-thiazol-2-yl ethyl urea
1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea
C24H24N4O5S
SHPFDGWALWEPGS-UHFFFAOYSA-N
9869779
CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC

Spezifikation

Ki 20227
623142-96-1
1-4-6,7-dimethoxyquinolin-4-yl oxy-2-methoxyphenyl-3-1-thiazol-2-yl ethyl urea, 1-4-6,7-dimethoxyquinolin-4-yloxy-2-methoxyphenyl-3-1-thiazol-2-yl ethyl urea, 1-4-6,7-dimethoxyquinolin-4-yl oxy-2-methoxyphenyl-3-1-1,3-thiazol-2-yl ethyl urea, pubchem22465, d08bjr, n-4-6,7-dimethoxy-4-quinolinyl o xy-2-methoxyphenyl-n'-1-2-thiazolyl ethyl urea, n-4-6,7-dimethoxy-4-quinolinyl oxy-2-methoxyphenyl-n'-1-2-thiazolyl ethyl urea, n-4-6,7-dimethoxy-4-quinolyl oxy-2-methoxyphenyl-n'-1-1,3-thiazol-2-yl ethyl urea
CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
480.539
480.54
50mg
C24H24N4O5S
SHPFDGWALWEPGS-UHFFFAOYSA-N
1-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-methoxyphenyl]-3-[1-(1,3-thiazol-2-yl)ethyl]urea
9869779
>97%
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