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![Human LRRK2 [D1994A], GST Tag Recombinant Protein 10μg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Human LRRK2 [D1994A], GST Tag Recombinant Protein
Human LRRK2 [D1994A], GST Tag Recombinant Protein
Marke: Invitrogen PV6051
Weitere Details : Netto-Gewicht : 0.50000kg
Beschreibung
LRRK2 is a multidomain protein that includes a kinase domain, a GTPase domain, and a leucine-rich repeat (LRR) domain. Certain mutations (e.g. I2020T, G2019S, and R1441C) in this gene have been associated with Parkinson's disease. D1994A is an artificial mutation that renders the kinase catalytically inactive and thus serves as a useful control for activity assays, especially when testing novel substrates.Related Links:
Spezifikation
| NP_940980.2 | |
| 120892 | |
| 10 μg | |
| LRRK Kinase Family | |
| Human | |
| Kinase proteins are shipped on dry ice and should be stored at -80°C. | |
| Ser⁄Thr Kinases: TKL Group | |
| LRRK2 D1994A | |
| Baculovirus | |
| Catalytic, Mutant, Inactive | |
| Signal Transduction, Neurobiology |
| Kinase Assay | |
| 205 kDa | |
| LRRK2 D1994A | |
| aa 970-2527 | |
| GST Tag | |
| Biochemical terbium phospho-specific activity, Biochemical binding/kinetic | |
| Dry Ice | |
| LRRK2 | |
| Kinases & Inhibitors | |
| Serine/Threonine Kinases |