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LRRK2-IN-1, Tocris Bioscience™

Potent and selective LRRK2 inhibitor

Marke:  RD Systems (Bio-Techne) 4273/50

Weitere Details : Netto-Gewicht : 0.00050kg

Menge. 50mg

 Weitere Artikel aus diesem Sortiment

Artikelnummer. 13414474

  • 1337.53 € / 50 Milligramm


Voraussichtlicher Liefertermin 02-05-2019
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Potent and selective inhibitor of leucine-rich repeat kinase 2 (LRRK2). Inhibits both G2019S mutant and wild-type LRRK2 kinase activity (IC 50 values are 6 and 13 nM respectively). Causes dephosphorylation, ubiquitination and degradation of LRRK2.
Spezifikation

Chemische Identifikatoren

1234480-84-2
570.698
lrrk2-in-1, lrrk2in1, lrrk2-in1, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidine-1-carbonyl phenyl amino-5,11-dimethyl-5h-benzo e pyrimido 5,4-b 1,4 diazepin-6 11h-one, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidine-1-carbonyl phenyl-amino-5,11-dimethyl-5h-benzo e pyrimido 5,4-b 1,4 diazepin-6 11h-one, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidine-1-carbonyl anilino-5,11-dimethylpyrimido 4,5-b 1,4 benzodiazepin-6-one, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidin-1-yl carbonyl phenyl amino-5,11-dimethyl-5,11-dihydro-6h-pyrimido 4,5-b 1,4 benzodiazepin-6-one, 5,11-dihydro-2-2-methoxy-4-4-4-methyl-1-piperazinyl-1-piperidinyl carbonyl phenyl amino-5,11-dimethyl-6h-pyrimido 4,5-b 1,4 benzodiazepin-6-one, lrrk-2in1, lrrk2-tn-1
CHEBI:78413
CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC
C31H38N8O3
IWMCPJZTADUIFX-UHFFFAOYSA-N
46843906
2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one

Spezifikation

LRRK2-IN-1
1234480-84-2
lrrk2-in-1, lrrk2in1, lrrk2-in1, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidine-1-carbonyl phenyl amino-5,11-dimethyl-5h-benzo e pyrimido 5,4-b 1,4 diazepin-6 11h-one, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidine-1-carbonyl phenyl-amino-5,11-dimethyl-5h-benzo e pyrimido 5,4-b 1,4 diazepin-6 11h-one, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidine-1-carbonyl anilino-5,11-dimethylpyrimido 4,5-b 1,4 benzodiazepin-6-one, 2-2-methoxy-4-4-4-methylpiperazin-1-yl piperidin-1-yl carbonyl phenyl amino-5,11-dimethyl-5,11-dihydro-6h-pyrimido 4,5-b 1,4 benzodiazepin-6-one, 5,11-dihydro-2-2-methoxy-4-4-4-methyl-1-piperazinyl-1-piperidinyl carbonyl phenyl amino-5,11-dimethyl-6h-pyrimido 4,5-b 1,4 benzodiazepin-6-one, lrrk-2in1, lrrk2-tn-1
CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC
570.698
CHEBI:78413
>98%
50mg
C31H38N8O3
IWMCPJZTADUIFX-UHFFFAOYSA-N
2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]anilino]-5,11-dimethylpyrimido[4,5-b][1,4]benzodiazepin-6-one
46843906
570.09
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