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PeproTech MCP-2 Polyclonal Antibody, PeproTech®, Invitrogen™

Artikelnummer. 17875123
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1 mg
100 μg
50 μg
Packungsgröße:
1 Milligramm
100 Mikrogramm
50 Mikrogramm
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17875123 100 μg 100 Mikrogramm
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Artikelnummer. 17875123 Lieferant PeproTech Lieferanten-Nr. 500P35100UG

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Beskrivelse

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MCP-2 (CCL8). Anti-Human MCP-2 (CCL8)-specific antibody was purified by affinity chromatography employing an immobilized Human MCP-2 (CCL8) matrix. Sandwich ELISA: To detect Human MCP-2 (CCL8) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human MCP-2 (CCL8) (500-P35Bt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human MCP-2 (CCL8). Western Blot: To detect hMCP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hMCP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
TRUSTED_SUSTAINABILITY

Tekniske data

Antigen MCP-2
Anwendungen ELISA, Western Blot
Klassifikation Polyclonal
Konzentration 0.1-1.0 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with no preservative
Gen CCL8
Gen-Zugriffsnummer P80075
Gen-Alias 1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8
Gensymbole CCL8
Wirtsspezies Rabbit
Immunogen E.coli-derived Recombinant Human MCP-2 (CCL8).
Reinigungsverfahren Antigen affinity chromatography
Menge 100 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 6355
Zielspezies Human
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Lyophilized
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