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Invitrogen™ Human MET (cMET) [Y1235D], GST Tag Recombinant Protein

Artikelnummer. 17108845
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1 mg
10 μg
100 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
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Artikelnummer. Menge unitSize
17108845 1 mg 1 Milligramm
15920413 10 μg 10 Mikrogramm
17168815 100 μg 100 Mikrogramm
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Artikelnummer. 17108845 Lieferant Invitrogen™ Lieferanten-Nr. A33728

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Beschreibung

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This MET (cMET) Y1235D recombinant human protein (956-end) was expressed in insect cells. MET (cMET) Y1235D recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Z'-LYTE™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Active, Cytoplasmic, Mutant The gene accession number for MET (cMET) [Y1235D] is NP_000236.2.

MET receptor tyrosine kinase is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kDa (alpha) and 145 kDa (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue. Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion. MET (Y1235D) is one of the native mutant forms of MET.
TRUSTED_SUSTAINABILITY

Spezifikation

Zugriffsnummer P08581
Konzentration See Label
Zur Verwendung mit (Anwendung) Kinase Assay
Zusammensetzung 50mM tris HCl with 0.1mM EDTA, 150mM NaCl, 10mM glutathione, 25% glycerol, 0.25mM DTT, 0.1mM PMSF and no preservative; pH 7.5
Gen-ID (Entrez) 4233
Molekulargewicht 75.4 kDa
Name Human MET (cMET) [Y1235D], GST Tag
pH-Bereich 7.5
Reinigungsverfahren Purified
Menge 1 mg
Lagerungsbedingungen -80°C, Avoid Freeze/Thaw Cycles
Kennzeichnung RUO
Gen-Alias c-Met
Gebräuchliche Bezeichnung c-Met (Y1235D Mutant)
Gensymbol MET
Kinase-Familie METs (HGFRs)
Proteinlänge 956-1390
Produkttyp Protein
Konjugat Unconjugated
Spezies Human
Rekombinant Recombinant
Proteinmarkierung GST-tag
Sequenz 956-1390
Inhalt und Lagerung -80°C, Avoid Freeze/Thaw Cycles
Versandbedingung Dry Ice
Expressionssystem Insect cells
Proteinform Recombinant, Active, Cytoplasmic, Mutant
Form Liquid
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