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Invitrogen™ mGluR5 Polyclonal Antibody
Beschreibung
Positive Control: mouse brain, rat brain Predicted Reactivity: Human (81%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
Spezifikation
Spezifikation
| Antigen | mGluR5 |
| Anwendungen | Western Blot, Immunocytochemistry |
| Klassifikation | Polyclonal |
| Konzentration | 1.64 mg/mL |
| Konjugat | Unconjugated |
| Zusammensetzung | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gen | Grm5 |
| Gen-Zugriffsnummer | P31424, Q3UVX5 |
| Gen-Alias | 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86 |
| Gensymbole | Grm5 |
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