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MOCOS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 16395-1-AP-20UL

Weitere Details : Netto-Gewicht : 0.00010kg

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Artikelnummer. 16886004

  • 112.71 € / 20 Mikroliter

Voraussichtliches Versanddatum: 18-06-2021

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Beschreibung

Beschreibung

The autosomal domit cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure′ cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.
Spezifikation

Spezifikation

MOCOS
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q14CH1, Q96EN8
HMCS, MCS, MoCo sulfurase, MOCOS, molybdenum cofactor sulfurase, MOS
Rabbit
IgG
20 μL
-20°C
Primary
361300, 55034, 68591
Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
MOCOS
Liquid
Mocos
MOCOS Fusion Protein Ag9487
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat, Mouse
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation